Intercellular Adhesion

Soluble Intercellular Adhesion Molecule

Previous studies have suggested that intercellular ad¬ hesion molecule 1 (ICAM-1, CD54) may be involved in the pathogenesis ofasthma. In addition, a soluble form of ICAM-1 (sICAM-1) has been detected in increased concentrations in the sera of patients with certain in¬ flammatory conditions. To determine whether bron¬ chial asthma is associated with increased levels of sICAM-1 in serum and to as...

Intercellular Adhesion Molecule (ICAM)-1,

Intercellular Adhesion Molecule-1 Expression

Intercellular Adhesion Molecule-1 Deficiency

Intercellular Adhesion Molecule-5 Induces Dendritic Outgrowth by Homophilic Adhesion

Intercellular adhesion molecule-5 (ICAM-5) is a dendritically polarized membrane glycoprotein in telencephalic neurons, which shows heterophilic binding to leukocyte beta(2)-integrins. Here, we show that the human ICAM-5 protein interacts in a homophilic manner through the binding of the immunoglobulin domain 1 to domains 4-5. Surface coated ICAM-5-Fc promoted dendritic outgrowth and arborizati...